Semaglutide
Hauv lub xyoo dhau los, kev lag luam tshuaj hypoglycemic tau hloov pauv.Raws li cov khoom tsim nyob rau hauv lub xyoo pua tshiab, GLP-1 analogs tau dhau los ua lub hnub qub dazzling tshaj plaws nyob rau hauv lub tshav pob ntawm hypoglycemic nrog qhov zoo ntawm cov nyhuv hypoglycemic zoo heev thiab zoo yuag poob.Ntawm lawv, kev poob phaus tau dhau los ua lwm qhov kev lag luam loj tshaj plaws rau cov tshuaj GLP-1.Tam sim no, cov qauv kev sib tw ntawm cov players loj uas tsom GLP-1 receptor agonists hauv tsev thiab txawv teb chaws tau maj mam "kub".Peb yuav tos thiab saib leej twg yuav ua tus coj thiab txeeb lub khw.
Kev txhaj tshuaj Semaglutide, yog ib hom tshiab ntawm cov ntshav qabzib ntev-1 (GLP-1) receptor agonist, uas muaj cov tshuaj insulin ntau lawm thiab kev ua haujlwm ntawm inhibiting qhov tso tawm ntawm pancreatic hyperglycemia, cov tshuaj zoo sib xws kuj tseem muaj txiaj ntsig rau Lutan peptide, ductal. peptide, thiab lwm yam.
Thaum Lub Kaum Ob Hlis 2017, US Food and Drug Administration (FDA) tau pom zoo cov npe ntawm Smeglugan peptide txhaj rau kev tswj hwm kev noj haus thiab kev tawm dag zog los txhim kho cov ntshav qabzib tswj cov neeg mob ntshav qab zib hom 2.Tsis tas li ntawd, Novo thiab Nord kuj tau tsim kho qhov ncauj noj hom Rybelsus ntawm Smeglugin, thiab tau pom zoo thawj zaug los ntawm FDA thaum lub Cuaj Hlis 2019. Qhov no kuj yog lub ntiaj teb thawj zaug pom zoo qhov ncauj GLP-1 tshuaj.ntshav qab zib.Hauv cov ntsiab lus, Smeglugin yog cov tshuaj hypoglycemic, tab sis vim tias cov tshuaj xws li Smeglugin peptide tuaj yeem ua rau lub plab khoob thiab txo qis qab los noj mov, nws yuav txo qhov hnyav.
Raws li qhov pom ntawm qhov no, thaum Lub Rau Hli 2021, FDA tau lees paub qhov kev tswj hwm qhov hnyav ntev ntawm kev rog lossis cov neeg laus rog rog.Cov neeg siv tau yog: cov neeg mob yooj yim nrog BMI ≥30 kg / m2;thiab BMI> 27 kg / m2 thiab sib koom ua ke tsawg kawg ib qho teeb meem rog rog, xws li kub siab, ntshav qab zib hom 2, lossis ntshav lipids txawv txav.Nws kuj yog qhov kev pom zoo no tias qhov kev ua yeeb yam tau muab faus rau Smeglugin ntawm txoj kev ntawm "cov tshuaj poob phaus".
Thaum lub Plaub Hlis 2021, Smegugan tau pom zoo hauv Suav teb rau kev tswj ntshav qab zib rau cov neeg mob ntshav qab zib hom 2 (T2DM).Txawm hais tias qhov ntsuas qhov hnyav tsis tau pom zoo hauv Suav teb, qhov kev thov rau kev poob phaus hauv tsev tsis tuaj yeem tuav hauv Suav teb.Tsis tas li ntawd, lub ntsiab lus tseem ceeb ntawm "thinness nrog thinness", nyob rau hauv ib nrab ntawm 2022, Smeglugin peptide "tsis pom zoo" hauv kev poob phaus., Ib zaug ntawm ntau lub lag luam e-lag luam, nws tau teeb tsa lub boom hauv kev yuav khoom, thiab ib zaug dhau los ua tus nqi siab "tawm ntawm huab tais huab tais", uas ncaj qha coj mus rau cov teeb meem ntawm cov tuam txhab tsim khoom thiab cov khoom siv.Nuo thiab Nord Lub Xya Hli xyoo tas los tau hais tias Kev rov pib kho tshuaj yuav tsum txwv tsis pub cov khoom lag luam tawm hauv tsev kho mob.
Qhov nrov ntawm Smegugu peptide kuj tau lees paub los ntawm Nuo thiab Nord cov ntaub ntawv nyiaj txiag.Raws li cov txiaj ntsig tsis ntev los no 2022 tshaj tawm los ntawm Nuo thiab Nord, cov nyiaj tau los txhua xyoo ntawm Nuo thiab Nord's GLP-1 kev lag luam yog 83.371 billion Dan Ying Crown (sib npaug li 81.6 billion yuan), nce 56% xyoo-rau-xyoo.Ntawm lawv, Smeglugin kev muag khoom yog 59.75 billion Dan Ying Crown (sib npaug li 58.5 billion yuan), nce 77% xyoo-rau-xyoo.Kev muag khoom ntawm GLP-1 cov khoom lag luam hauv kev kho mob ntshav qab zib hom 2 hauv Suav teb tau nce 102% hauv Dan Ying Krone.
Tau kawg, qhov tawg ntawm Smeglugin hauv kev poob phaus yog ze ze rau nws cov txiaj ntsig tseem ceeb."Nws yog lub sij hawm noj, haus thiab haus, noj 5 phaus hnyav, poob 30 phaus nyob rau hauv Lub ib hlis ntuj" thiab hais txog.Tsis tas li ntawd, "dag tiaj" tuaj yeem ua nyias, uas tau nyiam ntau lub qhov muag rau Smegtu peptides, ib zaug hu ua "cov tshuaj poob phaus".Txawm li cas los xij, qee tus kws kho mob tau hais tias Simei Gulu peptide muaj ntau dua 2/3 ntawm kev muag khoom hauv Suav teb kom poob phaus, tsis yog ntshav qab zib.Ntawm ib sab Hais txog Smeglugan peptide raws li cov tshuaj noj, muaj cov kev phom sij zais cia hauv kev nyab xeeb ntawm cov tshuaj superpatient.
Nws yog tsim nyog sau cia tias cov kev tshawb fawb hauv tsev cov lus xaus ntawm cov tshuaj no yog los ntawm cov neeg laus cov neeg rog rog loj.Rau cov neeg uas muaj roj me ntsis lossis hnyav hnyav (BM <27kg/m2), cov txiaj ntsig thiab kev pheej hmoo tseem tsis tau paub.Tsis tas li ntawd, ntxiv rau cov tshuaj tiv thaiv hypoglycemia uas yog cov tshuaj hypogenal uas tshwm sim hauv cov tshuaj hypoglycemic, cov tshuaj tiv thaiv kab mob plab yog qhov tseem ceeb, thiab qhov tshwm sim ntawm xeev siab, cem quav, ntuav thiab raws plab yog siab li 82.8%.7%.Qhov tseem ceeb tshaj plaws yog tias Smeglugin tsis tau txais kev pom zoo rau kev poob phaus hauv Suav teb.Qhov teeb meem ntawm cov tshuaj raws thiab kev siv yeeb tshuaj ntawm cov neeg zoo li no yog tsim nyog rau kev mloog.
Post lub sij hawm: Aug-23-2023
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