ua Tuam Tshoj 87512-31-0 Fluorene methoxy carbonyl-L-ALANYL-L-ALANINE Chaw tsim tshuaj paus thiab Hoobkas |Jiayinglai
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87512-31-0 Fluorene methoxy carbonyl-L-ALANYL-L-ALANINE

87512-31-0 Fluorene methoxy carbonyl-L-ALANYL-L-ALANINE Featured duab
  • 87512-31-0 Fluorene methoxy carbonyl-L-ALANYL-L-ALANINE
  • 87512-31-0 Fluorene methoxy carbonyl-L-ALANYL-L-ALANINE
  • 87512-31-0 Fluorene methoxy carbonyl-L-ALANYL-L-ALANINE

87512-31-0 Fluorene methoxy carbonyl-L-ALANYL-L-ALANINE

Lus piav qhia luv luv:

Qhov tshwm sim Dawb rau Off-White crystals los yog crystalline hmoov.
MF C21H22N2O5
MW 382.41 ib
Purity 98+


Product Detail

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Kev cia khoom:
Muab ntim rau hauv qhuav, 2-8 ° C

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Ntawv pov thawj:
COA, HPLC, GC, HNMR, Assay, Dej Cov ntsiab lus (KF), TLC muaj

D-Lys(tfa)-NCA (2)

Synonyms

FMOC-ALA-ALA-OH;
Fmoc-L-Ala-L-Ala-OH;
(S)-2-((S)-2-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)propanamido)propanoic acid;
Fmoc-Ala-Ala-OH99%;
FMoc-Ala-Ala;
FMOC-ALA-ALA-OH;
FMOC-L-ALANYL-L-ALANINE;
FMoc-AA-OH;
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-alanine

Ntim sab hauv

Lawv feem ntau yog siv los ntim cov hmoov.Thiab lawv tuaj yeem tiv thaiv tshav ntuj thiab dej kom tsis txhob ua phem.

sab nrauv ntim

Lub thawv tawv tawv tuaj yeem tiv thaiv koj cov khoom los ntawm kev sib tsoo thiab ntub dej.

Daim ntawv thov

Cov khoom no yog polypeptide muaj li ntawm 28 amino acids.Rau N - acetyl - L - silk ammonia acyl - L - alpha amino ammonia acyl - L - propylene ammonia acyl - L - propylene ammonia acyl - L - valerian ammonia acyl - L - alpha amino ammonia acyl - L - Sue ammonia acyl - L -Ammonia acyl - L - hlau ammonia acyl - L - alpha glutamine - L - txawv lub teeb ammonia acyl - L - Sue ammonia acyl - L - Sue ammonia acyl - L - lai ammonia acyl - L - alpha amino ammonia acyl - L - Lub teeb ci ammonia acyl - L - lai ammonia acyl - L - alpha - glutamine - L - lai ammonia acyl - L - lai ammonia acyl - L - alpha glutamine - L - valerian ammonia acyl - L - valerian ammonia acyl - L - alpha glutamine - L - alpha - glutamine - L - propylene ammonia cawv - L - alpha - glutamine - L - asparagine.Raws li kev suav cov tshuaj anhydrous thiab acetic acid-dawb, thymus muaj txoj kev (C129 H215 N33O55) yuav tsum yog 95.0% ~ 105.0%.
Cov khoom no yog dawb los yog dawb hmoov los yog xoob loj.
Cov khoom no yog yaj hauv trifluoroacetic acid, me ntsis soluble hauv dej, insoluble hauv acetonitrile, ether thiab trichloromethane.
Noj cov khoom no, ntsuas nws kom raug, ntxiv 0.02mol / L phosphate buffer tov (pH 7.0) ( noj 2.72g potassium dihydrogen phosphate, ntxiv 0.1mol / L sodium hydroxide tov 116.4ml kom yaj, dilute nrog dej rau 1000ml) thiab ua ib tug Cov tshuaj muaj txog 5mg hauv txhua 1 ml.Txiav txim siab raws li txoj cai lij choj (Appendix ⅥE ntawm Tshooj II ntawm Pharmacopoeia, 2010 tsab), cov curl tshwj xeeb yuav tsum yog -100.0 ° txog -110.0 ° raws li kev suav cov tshuaj tsis muaj dej thiab acetic acid.
Lub mechanism ntawm kev txiav txim ntawm cov khoom no nyob rau hauv kev kho mob kab mob siab B thiab txhim kho lub cev tsis muaj zog reactivity tsis tau elucidated tag nrho.Ntau qhov kev sim hauv vitro tau pom tias cov khoom no tuaj yeem txhawb kev loj hlob ntawm T lymphocytes los ntawm kev txhawb nqa cov mitogen ntawm peripheral ntshav lymphocytes, nce qib ntawm interferon α, interferon γ, interleukin 2, interleukin 3 thiab lwm yam lymphatic yam secreted los ntawm T hlwb. Tom qab ua kom cov antigen los yog mitogen, thiab nyob rau tib lub sij hawm nce qib ntawm lymphofactor receptors nyob rau saum npoo ntawm T hlwb.Nws tseem tuaj yeem txhim kho cov lus teb ntawm allogeneic thiab autologous tib neeg sib xyaw lymphocytes los ntawm kev ua kom CD4 hlwb.Cov khoom no tuaj yeem ua rau muaj kev sib sau ua ntej NK hlwb, thiab interferon tuaj yeem ua rau lawv cov cytotoxicity.Hauv vivo kev sim pom tias cov khoom no tuaj yeem nce qib kev qhia ntawm interleukin-2 receptor thiab qib zais cia ntawm interleukin-2 hauv nas lymphocytes tom qab cancanadin A ua kom.

cov khoom muaj feem xyuam

Gly-Ala-Ome.hcl Fmoc-L-Ala-OH β-Ala-Ome.HCl L-Ala-Ph-OH
Gly-Gly-Ala-Ome.hcl Fmoc-DL-Ala HL-Ala-Ome.Hcl L-Ala-Leu-OH
L-ALA Fmoc-D-Ala-OH β-Ala-Otbu.HCl L-Ala-Pro-OH
DL-UA Fmoc-β-Ala-OH DL-Ala-Otbu.Hcl DL-Ala-DL-Val
H-Ala-ol Fmoc-LN-Me-Ala-OH L-Ala-NH2.HCl Ala-Gly-Ome.hcl
β-Ala-ol Fmoc-N-Me-D-Ala-OH HD-Ala-NH2 · HCl L-Ala-Ala-Obzl.HCl
D-ALa Fmoc-Ala-Cl HD-Ala-NH2 D-Ala-D-Ala-Ome.Hcl
H-β-Ala-OH Fmoc-L-Ala-Ol Ac-L-Ala-NH2 H-Ala-Ala-Otbu.HCL
HN-Me-L-Ala-OH fmoc-β-Ala-NH2 Ac-D-Ala-NH2 Boc-Ala-Ph-OH
HN-Me-D-Ala-OH Fmoc-Ala-Ome AC-D, L-Ala-OH Boc-L-Ala-Leu
L-Ala-NCA Fmoc-Ala-Osu Ac-D-Ala-OH Boc-ALa-Val-OH
D-Ala-NCA fmoc-β-Ala-osu AC-L-Ala-OH Boc-Ala-Pro
L-Ala-nbu.hcl Cbz-L-Ala-OH AC-L-Ala-OME Boc-Ala-Gly-OH
L-Ala-Otbu Cbz-D-Ala-OH Pht-D-Ala Boc-Ala-Ala-OH
D-ALA-Oipr.HCL Cbz-N-Me-L-Ala-OH Pht-L-Ala Boc-Ala-Ala-Ome
D-Ala-Otbu.Hcl Cbz-N-Me-D-Ala-OH Boc-L-Ala-OH Boc-Ala-Ala-Obzl
N-Me-L-Ala-OMe Cbz-DL-Ala-OH Boc-D-Ala-OH Fmoc-Ala-pro
HD-Ala-OBzl · HCl Z-β-L-Ala-OH Boc-DL-Ala-OH Fmoc-Ala-gly-OH
β-Ala-Obzl.Tos Cbz-L-Ala-OL Boc-β-Ala-OH Fmoc-L-Ala-Ala-OH
H-Ala-OBzl · HCl Cbz-L-Ala-NH2 Boc-N-Me-Ala-OH Fmoc-β-Ala-D-phe
HL-Ala-OBzl.Tos-OH Cbz-L-Ala-Ome Boc-N-Me-DL-Ala-OH Fmoc-β-Ala-D-Tyr (Et)
HD-Ala-Oet.HCl Cbz-D-Ala-OMe Boc-N-Me-D-Ala-OH Cbz-Ala-Val-OH
HL-ALA-Oipr.HCL Cbz-Beta-Ala-Ome Boc-L-Ala-Ol Cbz-L-Ala-Ala-OH
N-Me-Ala-Otbu.Hcl Cbz-β-Ala-Otbu Boc-D-Ala-Ol Cbz-Ala-Pro-OH
HL-Ala-OtBu · HCl Cbz-L-Ala-Osu Boc-DL-Ala-Ol Cbz-L-Ala-Leu-OH
H-DL-Ala-OMe.HCl Cbz-Beta-Ala-OSU Boc-Ala-NH2 Cbz-L-Ala-Ala-Ome
β-Ala-Oet.HCl Ala-Ala-OH Boc-D-Ala-NH2 Ala-Ala-Ome.HCL
N-Me-L-Ala-Ome.hcl Ala-gly Boc-β-Ala-NH2 Val-Ala
HD-Ala-Ome.Hcl L-ALA-Val-OH Boc-D-4-Chloropheny (Alanine) Boc-Ala-Pro
Boc-L-ALA-OBZL Boc-Leu-Ala Boc-D-3 (1-Naphthgl)-alanine Boc-Val-Ala
Boc-L-Ala-OSu Fmoc-leu-ala Boc-L-Ala-Ome Cbz-Val-Ala-OH
Boc-L-Beta-Ala-Osu Cbz-Leu-Ala-OH Boc-D-Ala-OMe Cbz-Val-Ala-Ome
Boc-D-Ala-OSu Pheej-Ala Boc-L-Ala-Otbu Leu-Ala-OH
Fmoc-L-Ala-OH.H2O Boc-Phe-Ala-OH Z-Lys(boc)-Ala-Ala-OBzl HL-Thr-OBzl · oxalate
HL-Thr(Bzl)-OBzl.oxalate Cbz-Ph-Ala-OH  

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