Card bei oxytocin (Carbetocin) yog ib hom kev sib txuas ntawm kev ua haujlwm ntev nrog cov yam ntxwv ntawm agonist oxytocin 8 peptide cov ntsiab lus, nws cov chaw kho mob thiab chaw muag tshuaj zoo ib yam li ntuj tsim oxytocin.Zoo li oxytocin, cabetin khi rau oxytocin receptors nyob rau hauv cov nqaij ntshiv ntawm lub tsev menyuam, ua rau lub tsev menyuam muaj zog, ua rau nws zaus thiab ua rau lub tsev menyuam nce ntxiv ntawm qhov qub contractions.Qib ntawm oxytocin receptors nyob rau hauv lub tsev menyuam yog tsawg thaum tsis xeeb tub thiab nce thaum cev xeeb tub, peaking thaum yug los.Yog li ntawd, cabetin tsis muaj kev cuam tshuam rau lub tsev menyuam uas tsis yog cev xeeb tub, tab sis muaj txiaj ntsig zoo ntawm uterine contractions ntawm lub tsev menyuam thiab lub tsev menyuam tom qab yug menyuam.Ob leeg intravenously los yog intrintrally, lub tsev menyuam tau cog lus sai, ncav cuag lub zog meej hauv 2 feeb.Ib koob tshuaj txhaj tshuaj capetin yog siv rau hauv lub tsev menyuam li ib teev, uas yog txaus los tiv thaiv los ntshav tom qab yug me nyuam tam sim ntawd tom qab yug me nyuam.Qhov zaus thiab amplitude ntawm contractions tom qab yug me nyuam ntawm carpetine tau ntev tshaj li ntawm oxytocin.Cov kev tshawb fawb tau pom tias thaum muab ib koob tshuaj ntawm 100μg txhaj tshuaj tam sim ntawd tom qab kev phais mob nyob rau hauv epidural lossis lumbar tshuaj loog, carbetin yog qhov zoo tshaj rau cov placebo hauv kev tiv thaiv uterine hypotonia thiab txo cov ntshav tom qab yug menyuam.Carpetine muab rau thaum ntxov postpartum lub sij hawm kuj yuav txhawb uterine rov qab.
Cabetin khi rau oxytocin receptors nyob rau hauv cov nqaij ntshiv ntawm lub tsev menyuam kom ua rau lub tsev menyuam sib cog lus, ua rau nws zaus ntawm contraction thiab nce uterine nro.Ib koob tshuaj carbetin tuaj yeem muab tam sim ntawd tom qab yug menyuam hauv plab kom tsis txhob los ntshav tom qab yug menyuam.Nws tau pom tias kev txhaj tshuaj oxytocin tom qab yug me nyuam ua ke nrog kev tswj hwm ntawm cabetin tuaj yeem tiv thaiv kev poob ntshav tom qab yug menyuam.Tom qab phais tas, kev siv cov cabetin ua ke nrog oxytocin tuaj yeem ua kom muaj zog ntawm lub tsev menyuam, txo cov ntshav poob tom qab phais, cov nyhuv tseem zoo dua li hemabate.Rau cov poj niam uas muaj cicatritic uterus, placenta previa thiab lwm yam kev pheej hmoo siab rau kev mob ntshav qab zib tom qab yug me nyuam, carbetin tuaj yeem tiv thaiv qhov tshwm sim ntawm cov ntshav tom qab yug me nyuam.Nws yog siv rau elective epidural los yog lumbar anesthesia tom qab phais tas los tiv thaiv uterine contraction tsis muaj zog thiab postpartum hemorrhage.