Peptide Synthesis thiab Hloov Kho: N-Me-L-Leu tuaj yeem siv los ua lub tsev thaiv hauv cov khoom sib txuas peptide.Nws tso cai rau kev qhia txog cov pab pawg methyl ntawm nitrogen txoj hauj lwm ntawm leucine, uas tuaj yeem hloov kho cov khoom siv physicochemical thiab kev ua haujlwm lom neeg ntawm cov txiaj ntsig peptides.Qhov kev hloov kho no tuaj yeem txhim kho peptide ruaj khov, hloov kho nws cov kev cuam tshuam nrog lwm cov molecules, lossis cuam tshuam nws lub hom phiaj ntawm tes.
Kev tshawb fawb Proteomics: Hauv kev tshawb fawb proteomics, N-Me-L-Leu tuaj yeem siv los ua cov ntawv sau npe reagent rau cov protein ntau lossis raws li kev soj ntsuam los tshawb xyuas cov protein-protein kev sib cuam tshuam.Cov pab pawg methyl tuaj yeem muab cov cim loj tshwj xeeb uas tuaj yeem kuaj pom los ntawm huab hwm coj spectrometry, ua kom muaj kev soj ntsuam ntau ntawm cov protein hauv cov sib tov sib xyaw.
Kev Tshawb Nrhiav Tshuaj thiab Kev Txhim Kho: N-Me-L-Leu muaj peev xwm siv tau hauv kev tshawb nrhiav tshuaj thiab kev loj hlob.Nws tuaj yeem muab tso rau hauv cov neeg sib tw tshuaj los hloov kho lawv cov kev ua haujlwm lom neeg, solubility, lossis pharmacokinetic zog.Cov pab pawg methyl tuaj yeem cuam tshuam qhov kev sib txuas ntawm cov tshuaj rau nws lub hom phiaj, txhim kho nws cov cell permeability, lossis hloov nws cov metabolic stability.
Cov Khoom Siv Hluav Taws Xob thiab Cov Khoom Siv Hluav Taws Xob: N-Me-L-Leu tuaj yeem sib txuas rau fluorescent dyes, radiolabels, lossis lwm yam khoom siv los tsim cov tshuaj lom neeg lom neeg lossis cov duab thaij duab.Cov kev sojntsuam no tuaj yeem siv los ua kom pom lossis ntsuas cov txheej txheem lom neeg tshwj xeeb hauv cov hlwb lossis cov ntaub so ntswg, muab kev nkag siab txog kev ua haujlwm ntawm tes thiab kab mob.
Khoom noj khoom haus ntxiv: Hauv kev noj zaub mov, N-Me-L-Leu tuaj yeem muaj peev xwm ua cov khoom noj khoom haus ntxiv lossis cov khoom xyaw hauv cov zaub mov ua haujlwm.Leucine yog ib qho tseem ceeb amino acid koom nrog hauv cov protein synthesis thiab cov leeg nqaij metabolism.Cov methylated derivative tuaj yeem muab cov txiaj ntsig tshwj xeeb ntsig txog nws txoj kev txhim kho bioavailability lossis hloov cov teebmeem metabolic.