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Tom ntej: 15260-10-3 Tert-butoxycarbonyl-L-threonine (benzyl)-OH

15260-10-3 Tert-butoxycarbonyl-L-threonine (benzyl)-OH Featured duab
  • Tom ntej: 15260-10-3 Tert-butoxycarbonyl-L-threonine (benzyl)-OH
  • Tom ntej: 15260-10-3 Tert-butoxycarbonyl-L-threonine (benzyl)-OH
  • Tom ntej: 15260-10-3 Tert-butoxycarbonyl-L-threonine (benzyl)-OH

Tom ntej: 15260-10-3 Tert-butoxycarbonyl-L-threonine (benzyl)-OH

Lus piav qhia luv luv:

Qhov tshwm sim Dawb rau Off-White crystals los yog crystalline hmoov.
MF C16H23NO5
MW 309.36 ib
Purity 98+


Product Detail

Kev thauj mus los & kev pom zoo shipping txoj kev:
los ntawm huab cua, los ntawm hiav txwv lossis los ntawm kev nthuav qhia

Kev cia khoom:
Khaws nyob rau hauv qhov chaw tsaus, kaw hauv qhuav, Chav Kub

Yam tsawg kawg nkaus Order Qty:
Kev sib tham

Ntawv pov thawj:
COA, HPLC, GC, HNMR, Assay, Dej Cov ntsiab lus (KF), TLC muaj

D-Lys(tfa)-NCA (2)

Synonyms

Boc-O-Benzyl-L-threonine;
BOC-THR-OH;
BOC-THR(BZL)-OH;
Butoxacarbonylbenzylthreonine;
NT-boc-O-benzyl-L-threonine * crystalline;
O-benzyl-N-tert-butoxycarbonyl-L-threonine;
N-ALPHA-T-BUTYLOXYCARBONYL-O-BENZYL-L-THREONINE;
NALPHA-tert-Butoxycarbonyl-O-benzyl-L-threonine

Ntim sab hauv

Lawv feem ntau yog siv los ntim cov hmoov.Thiab lawv tuaj yeem tiv thaiv tshav ntuj thiab dej kom tsis txhob ua phem.

Sab hauv ntim 2
Inner packing 1
Inner packing 3

sab nrauv ntim

Lub thawv tawv tawv tuaj yeem tiv thaiv koj cov khoom los ntawm kev sib tsoo thiab ntub dej.

Kev ntim khoom sab nrauv 3
Kev ntim khoom sab nrauv 2
Kev ntim khoom sab nrauv 1

Daim ntawv thov

Dawb crystalline hmoov;Insoluble hauv dej thiab roj av ether, soluble hauv ethyl acetate thiab methanol;mp yog 115-116 ℃;Kev sib hloov tshwj xeeb [α]20D + 15.8 ° (0.5-2.0 mg / ml, methanol).
Siv rau polypeptide synthesis, ua cov amino acid tiv thaiv monomer.
O-benzyl-l-threonine raug tshem tawm hauv cov tshuaj dioxane thiab acylated nrog tert-butylcarbonyl azide kom tau txais cov khoom siv raw, uas tau muab rho tawm los ntawm ethyl acetate ntawm pH ntawm 9-10 thiab tom qab ntawd recrystallized.
Ib feem ntawm thymic oietin Ⅱ ntawm thymus secretions.Thymoietin II yog ib qho polypeptide compound cais los ntawm thymus hormone.Nws yog tsim los ntawm 49 amino acids, thiab peptide saw fragment muaj li ntawm 5 amino acids muaj tag nrho cov tib physiological functions li thymoietin II.Yog li ntawd, qhov no pentapeptide tawg yog hu ua thymus pentapeptide.Dawb freeze-dried xoob loj los yog hmoov.
Ib qho ntawm lub luag haujlwm ntawm thymus pentapeptide yog ua kom muaj kev sib txawv ntawm T cell.Nws tuaj yeem xaiv qhov kev hloov pauv ntawm Thy-1- prothorax hlwb rau hauv Thy-1 + T hlwb.Kev sib txawv ntawm T cell yog kho los ntawm kev nce qib cAMP hauv lub cev.Lwm txoj haujlwm tseem ceeb ntawm thymus pentapeptides yog khi rau cov receptors tshwj xeeb ntawm cov ntshav peripheral T hlwb, nce qib cAMP intracellular, thiab yog li ua rau muaj kev cuam tshuam ntawm intracellular, uas kuj yog lub hauv paus ntawm nws txoj haujlwm immunomodulatory.Nyob rau hauv lub cev ib txwm muaj, thymus pentapeptide tau pom lub cev tiv thaiv kab mob, uas tuaj yeem ua rau nce E rosette tsim tus nqi thiab hloov pauv tus nqi ntawm splenic lymphocytes, txhim kho cov theem sib txawv ntawm thawj lossis theem nrab tiv thaiv kab mob, thiab nce tus naj npawb ntawm IgM hom thiab IgG los yog IgA hom tshuaj tiv thaiv kab mob tsim cov hlwb.Thymus pentapeptide tuaj yeem txhim kho phagocytosis kev ua haujlwm ntawm macrophages, nce enzyme thiab phagocytosis muaj nuj nqi ntawm polymorphonuclear neutrophils, nce cov ntsiab lus ntawm cov tshuaj tiv thaiv kab mob, thiab txhim kho kev tiv thaiv kab mob ntawm cov ntshav liab.Thymus pentapeptide tuaj yeem qhib CD4 thiab CD8 cov hlwb zoo, yog li cov kab mob Tc tshwj xeeb tuaj yeem tuav lub neej ntev dua, tab sis kuj tuaj yeem qhib Th cells thiab ua rau muaj kev ua haujlwm ntawm Ts hlwb.Cov tshuaj tiv thaiv kab mob thiab kho cov teebmeem ntawm thymus pentapeptide muaj feem xyuam rau nws txoj kev txhim kho ntawm TC cell kev ua.Tus nqi tsim nyog ntawm thymus pentapeptide tuaj yeem ua rau muaj txiaj ntsig zoo ntawm interferon hauv kev tiv thaiv kab mob.Inducing thiab txhawb T cell sib txawv thiab maturation;CD4 / CD8 zoo li qub los ntawm kev tswj cov feem ntawm T lymphocyte subsets;Txhim khu kev ua haujlwm ntawm phagocytosis ntawm macrophages;Txhim kho cov ntshav liab tiv thaiv kab mob;Ua kom muaj kev ua haujlwm ntawm cov cell killer ntuj;Nce qib ntawm interleukin-2 ntau lawm thiab receptor qhia;Txhim khu kev tsim cov γ interferon hauv peripheral ntshav mononuclear hlwb;Txhim khu kev ua haujlwm SOD hauv cov ntshav.
Nws tuaj yeem siv tau rau cov neeg mob qog nqaij hlav uas tsis muaj zog tiv thaiv kab mob tom qab siv hluav taws xob thiab tshuaj tua kab mob.Kev kho kab mob siab B;Kev phais loj thiab kev kis mob hnyav;Cov kab mob autoimmune xws li mob caj dab rheumatoid, lupus erythematosus;Hom II mob ntshav qab zib mellitus, menopause syndrome;Ib tug neeg uas tsis muaj zog tiv thaiv kab mob.

cov khoom muaj feem xyuam

Fmoc-L-Thr(tBu)-Ph-OH Boc-D-Thr-OH
HL-Thr-OH Boc-D-Thr(me)-OH
DL-Thr Boc-D-Thr(Bzl)-OH
HL-allo-Thr-OH Cbz-Thr-OH
L-Thr (bzl) Cbz-Thr-Obzl
HL-Thr(tBu)-OH ZL-Thr-ome
L-Thr (kuv) Cbz-D-Thr-OH
Thr-Otbu.hcl Cbz-L-Thr(tBu)-OH
L-Thr(bzl).HCl Cbz-L-Thr(bzl)-OH
L-Thr(me).Hcl Cbz-L-Thr(tBu)-OH DCHA
L-Thr-Obzl.HCl Fmoc-L-Thr-OH
HL-Thr-OMe.HCl fmoc-L-Thr-OtBu
L-Thr-Oet.Hcl Fmoc-L-Thr-Obzl
L-Allo-Thr-Ome.Hcl Fmoc-L-Allo-Thr-OH
HL-Thr-OBzl·oxalate Fmoc-Thr(tBu)-OH
D-Thr(bzl).HCl Fmoc-L-Thr(bzl)-OH
D-Thr-Oet.Hcl Fmoc-D-Thr-OH
D-Thr-Obzl.HCl Fmoc-D-Thr(bzl)-OH
D-Thr-Ome.HCl Fmoc-D-Thr(tBu)-OH
DL-Thr-Ome.HCl Fmoc-L-Thr(tBu)-Ser-OH
Boc-L-Thr-OtBu Boc-n-me-l-thr(bzl).CHA
Boc-L-Thr-OH Fmoc-N-Me-L-Thr(bzl)-OH
Boc-L-allo-Thr-OH Fmoc-L-Thr(tBu)-Gly-OH
Boc-Thr-OMe (2S,3S)-2-Amino-3-methoxybutanoic acid/L-AlloThr(Me)
Boc-Thr-Obzl (2S,3S)-2-Amino-3-methoxybutanoic acid/BOC-AlloThr(Me)
Boc-L-Thr(tBu)-OH HL-Thr(Bzl)-OBzl.oxalate
Boc-L-Thr(Bzl)-OH Boc-D-Thr-Ome
Boc-L-Thr(me)-OH

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